The family of Anne Heche say the American actress “will be deeply missed but lives on through her beautiful sons” following a car crash in Los Angeles last week.
Under California law, Heche, 53, is legally dead but her family say they are keeping her heart beating and she has not been taken off life support as they seek a match for organ donation, in respect of her wishes.
The actress is known for roles in Donnie Brasco, Cedar Rapids and the 1998 Psycho remake.
Heche suffered significant burns and lung damage after crashing into a two-storey house in the Mar Vista area on the morning of Friday 5 August.
Preliminary blood tests showed “signs of narcotics” in her system and her family said she was “not expected to survive” after the collision left her in a coma.
The Los Angeles Police Department (LAPD) has said additional testing is required to rule out any substances that were administered in hospital.
In a statement her family said they had “lost a bright light, a kind and most joyful soul, a loving mother, and a loyal friend”.
More from US
Donald Trump being investigated under Espionage Act, with ‘top secret’ documents taken from his Florida home
Sir Salman Rushdie: Satanic Verses author stabbed in neck and abdomen at event in New York
Donald Trump calls for ‘immediate’ release of Florida warrant as attorney general says he personally approved FBI search
“Anne will be deeply missed but she lives on through her beautiful sons, her iconic body of work, and her passionate advocacy,” they added.
“Her bravery for always standing in her truth, spreading her message of love and acceptance, will continue to have a lasting impact.”
US talk show host Ellen DeGeneres, who dated Heche from 1997 to 2000, tweeted: “This is a sad day. I’m sending Anne’s children, family and friends all of my love”.
Heche previously said her relationship with DeGeneres was ground-breaking for the time because of the global attention they received as Hollywood stars in a same-sex romance.
While Nancy Davis, a friend of the actress, wrote on Instagram that “heaven has a new angel”.
“My loving, kind, fun, endearing and beautiful friend Anne Heche went to heaven. I will miss her terribly and cherish all the beautiful memories we have shared,” she said.
On Thursday Heche’s family issued a statement saying: “Unfortunately, due to her accident, Anne Heche suffered a severe anoxic brain injury and remains in a coma, in critical condition. She is not expected to survive.
“It has long been her choice to donate her organs and she is being kept on life support to determine if any are viable.”
Heche landed her first notable role on the soap opera Another World, portraying Vicky Hudson and Marley Love into the early 1990s.